Craig W. Stevens, M.D., Ph.D.
- Contact Address
- M. D. Anderson Cancer Center
The University of Texas
1515 Holcombe Blvd
Houston, TX - Professional Affiliations
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- M. D. Anderson Cancer Center
Position held: Associate Professor of Radiation Oncology
- M. D. Anderson Cancer Center
- Expertise
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- Mesothelioma
- Lung Tumor Hypoxia
- Lung Tumor Radiation Planning
- Board Certification
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- American Board of Radiology - Radiation Oncology, 1994
- Website
- Biography/CV (will open new window)
- Biography
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I have been active in both clinical and basic science research. My clinical research has focused primarily on cancers of the chest, particularly pleural mesothelioma where we are pioneering the use of post-operative Intensity Modulated Radiotherapy (IMRT), lung tumor hypoxia, lung tumor radiation treatment planning. I am principal investigator on three clinical protocols, one in each of these three areas.
My laboratory has also developed an assay for normal tissue radiosensitivity based on the profile of DNA binding proteins, which our patent office has agreed to file as a preliminary patent application with the US patent service. This assay may also predict chemosensitivity, and be a preliminary screen for BRCA heterozygocity. We are also studying the proteins involved in DNA dobule strand break repair (the subject of my current ACS grant $375,000 over 3 years). We have discovered that proteins from many DNA repair pathways interact to promote or impair DNA repair. For example, one protein complex has been isolated that contains ATM, RPA, XPA, p53, RAD51, BLM, WRN, and KU70/80.
