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Malignant pleural mesothelioma: evaluation with CT, MR
imaging, and PET.
Wang ZJ, Reddy GP, Gotway MB, Higgins CB,
Jablons DM, Ramaswamy M, Hawkins RA, Webb WR.
ABSTRACT
Imaging plays an essential role in the evaluation of malignant pleural
mesothelioma (MPM). Computed tomography is the primary imaging modality used for
the diagnosis and staging of MPM. Magnetic resonance (MR) imaging and, more
recently, positron emission tomography (PET) have emerged as modalities that can
provide additional important diagnostic and prognostic information to help
further delineate the extent of disease, especially in surgical candidates. Use
of MR imaging performed with different pulse sequences and gadolinium-based
contrast material can improve the detection of tumor extension, especially to
the chest wall and diaphragm. PET can provide both anatomic and metabolic
information, especially in cases of extrathoracic and mediastinal nodal
metastasis. Each imaging modality has its advantages and limitations, but their
combined use is crucial in determining the most appropriate treatment options
for patients with MPM. Copyright RSNA, 2004
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